https://kahnelab.chemistry.harvard.edu/contact daily 0.75 2025-09-02 https://kahnelab.chemistry.harvard.edu/overview daily 1.0 2018-10-04 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1533829819657-3IK4592I1RVSU6LUULZY/Ge-EM-4774-WT-582-2um002.jpg Overview https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1533852837882-MWEJFA1TND2NJYBWJ7O0/CellWall.png Overview - Cell wall biosynthesis https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1533852793535-07DM5EYZX8AE6LYIEJW6/Lipopolysaccharide.png Overview - Lipopolysaccharide transport https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1533852861299-XVGEEHDRYPHK169C7K7Y/OuterMembrane.png Overview - Outer membrane protein assembly https://kahnelab.chemistry.harvard.edu/cellwall daily 0.75 2018-12-27 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1539028656083-VM9VO18U39JWQRDFAQN7/TagT---v6---black-bg-wide.jpg Cell wall biosynthesis https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1536867167019-MWSIVHM0Z5PYO7M9R7VZ/Labeled_PG.png Cell wall biosynthesis - Cell wall overview Lipid II, the monomer for bacterial cell wall, is synthesized inside the cytoplasm and then flipped outward by the transporter MurJ. It is then polymerized by glycosyltransferases (GTs) and crosslinked by transpeptidases (TPs) to make the protective mesh that is cell wall. https://kahnelab.chemistry.harvard.edu/lps daily 0.75 2018-12-27 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1536894020699-URTEGJ8TEGS26Y2YQSSR/TS_MsbA_Dansyl_crop2.jpg Lipopolysaccharide transport https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1536866062910-MFFJCUDS6LV23G9UCQHK/Labeled_LPT.png Lipopolysaccharide transport - Lipopolysaccharide transport overview Lipopolysaccharide (LPS) is first synthesized in the cytoplasm and then is transported across the aqueous periplasm and through the outer membrane via a protein bridge. Our lab studies the mechanism of LPS transport to understand how to inhibit outer membrane biogenesis. https://kahnelab.chemistry.harvard.edu/outermembrane daily 0.75 2018-12-27 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1533849751601-NOX02A6GLL04OUJZ6P6R/2018-08-09+17.11.53.jpg Outer membrane protein assembly https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1536866163811-3C3IGKZ0I8MYFVBKOYI1/Labeled_BAM.png Outer membrane protein assembly - Outer membrane protein biogenesis Outer membrane beta-barrels are folded and inserted into the outer membrane by the Bam complex (BamABCDE). https://kahnelab.chemistry.harvard.edu/members daily 0.75 2026-03-23 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1734466596192-NMNG9EEMQLRFF26NY2B9/Group+Dec+2024+.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1538517898430-JT0NZR96MX7THSFZS03K/Dan.jpg Lab Members Dan Kahne Higgins Professor of Chemistry and Chemical Biology and of Molecular and Cellular Biology Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1538517914532-XQ8QPOHV5LFOEX3I9L66/mike.png Lab Members Mike Quinn Lab Administrator Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1538602573412-S0T9AMR8EXCCRSB552FU/Vadim.jpg Lab Members Vadim Baidin Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1639751597141-QM75WE2SW257YV6S2F78/unsplash-image-mdADGzyXCVE.jpg Lab Members Melissa LeGrand Faculty Assistant Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1632933789482-N5ZQDWZSKQNKEQ7OVTFM/Alessio_Caruso_KahnePortrait.JPG Lab Members - Make it stand out Alessio Caruso Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/6b77d7de-dce1-4f72-83c3-3d5148d101fd/IMG_5332.jpg Lab Members - Make it stand out Rosalie Doerksen Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/5230ec20-0244-4471-b67b-567219d705a7/ShelleyHe.jpg Lab Members Shelley He Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/03eac3ed-437a-4c48-bdc1-1a17aa4cc39a/MMarquez+photo.jpg Lab Members Melissa Marquez Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/99a310f0-fd73-4c92-af21-4d8ba6b9e664/IMG_4890.JPG Lab Members - Make it stand out Cait Moffatt Graduate Student, Molecules, Cells, and Organisms Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1632235533232-SLLB4OUDKU9S6UENRHHS/IMG_2590.png Lab Members Bailey Plaman Graduate Student, Chemical Biology Program Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/a205418a-45f3-4c8c-9e72-3cc92002f7da/Amber+Scharnow.jpg Lab Members Amber Scharnow Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1583352596766-P80YEUK334DYTA1QJLQZ/Stephen_Blur.jpg Lab Members Stephen Early Graduate Student, Chemical Biology Program Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/bdd4336f-9a0b-4012-ba59-bca62105f09d/Laura.Hwuang.2022_KatieMSimmons_-18953.jpg Lab Members - Make it stand out Laura Hwang Undergraduate Student, Class of 2027 Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/beaca728-4bac-42d6-ae91-d3b7e283d60b/Marina.jpg Lab Members Marina Monsivais Graduate Student, Chemistry and Chemical Biology Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1583352612769-DAYKDUB68ANBBINZ0SUE/Pengxiang_Blur.jpg Lab Members Pengxiang Shen Postdoctoral Fellow Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/2622be6e-04ea-48fe-a158-86c4055470f8/Liam.jpg Lab Members - Make it stand out Liam Spencer Undergraduate Student, Class of 2027 Email | Bio https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1774296528739-IYVXI6Y2AADO3TCKC3TK/unsplash-image-UGjaxpQnz8M.jpg Lab Members - - Email | Bio https://kahnelab.chemistry.harvard.edu/gallery daily 0.75 2025-06-06 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1766360910682-JYHNMHM6TYWYN21X0WV1/Unknown-2.jpeg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1766360894111-NCA3NC6QR6I7B4KOSH0N/Unknown.jpeg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1766361139566-9U6SMVKG4VGSX32GSWWP/img_6222_720.jpg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1746638867368-T6AYD0PDQ8JE89TRWSC4/IMG_5567.jpg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1756998989821-EWA6Y5XVWYKDGIFOVHW4/IMG_1934.jpg Gallery 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https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1578074036714-MRZ4BNU21IVRS6Z1S87U/IMG_5563.jpg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1578074065696-NJP01JZXFPPHAP3764O9/IMG_5568.jpg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1578074416185-SVE4CUWT8BZHREWUJK2B/crop1.jpg Gallery https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/1578074436355-9OXOLADH39Z1J2WS29SV/crop3.jpg Gallery https://kahnelab.chemistry.harvard.edu/alumni daily 0.75 2026-03-23 https://kahnelab.chemistry.harvard.edu/recent-events daily 0.75 2025-12-21 https://images.squarespace-cdn.com/content/v1/5b6c564e2714e5e63ba05a8a/bf1fcda4-fc1e-4976-bb46-88b5b4e94c4e/Unknown-1.jpg Recent Events - Make it stand out Recipient of the Doctor of Philosophy Sebastian Rowe, Chemical Biology 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